Low-Grade Serous Cancer Research Catalogue

How to access research

Below is a list of journal articles currently available through the international low-grade facebook page.
Membership is open to any woman with low-grade.
If you are a carer, family or friend you can access it through our support group for carers/family/friends of low-grade serous women.
You can find the articles in the facebook group by going to “Files” and selecting “The Library”. On mobile devices “Files” is located under “… More”/”View Group Info”.

Learn more about research and how to interpret it.

10 Significant Studies

  • Activity of bevacizumab-containing regimens in recurrent low-grade serous ovarian or peritoneal cancer: A single institution experience
  • Current status and future perspectives in low-grade serous cancer of the ovary
  • Low-Grade Serous Ovarian Cancer: Current Treatment Paradigms and Future Directions
  • Does tumor grade infuence the rate of lymph node metastasis in apparent early stage ovarian cancer?
  • Hormonal Maintenance Therapy for Women With Low-Grade Serous Cancer of the Ovary or Peritoneum
  • Immunosuppressive microenvironment in low-grade serous ovarian carcinoma
  • Outcomes of Women With High-Grade and Low-Grade Advanced-Stage Serous Epithelial Ovarian Cancer
  • Primary cytoreductive surgery and adjuvant hormonal monotherapy in women with advanced low-grade serous ovarian carcinoma: Reducing overtreatment without compromising survival?
  • Recurrent low-grade serous ovarian carcinoma is relatively chemoresistant
  • The role of secondary cytoreduction in low-grade serous ovarian cancer or peritoneal cancer

Reviews

  • Current status and future perspectives in low-grade serous cancer of the ovary
  • Low-Grade Serous Ovarian Cancer: Current Treatment Paradigms and Future Directions
  • Low Grade Serous Ovarian Carcinoma: From the molecular characterization to the best therapeutic strategy
  • Low grade serous ovarian carcinoma: identifying variations in practice patterns
  • Low-grade Serous Neoplasia of the Female Genital Tract
  • Préservation de la fertilité, contraception et traitement hormonal de la ménopause chez les femmes traitées pour tumeurs malignes rares de l’ovaire : recommandations du réseau national dédié aux cancers gynécologiques rares (TMRG/GINECO)
  • low-grade epithelial ovarian cancer: what a radiologist should know
  • Low-grade epithelial ovarian cancer: a number of distinct clinical entities?

Clinical Research

Case Studies

  • Binimetinib (MEK162) in recurrent low-grade serous ovarian cancer resistant to chemotherapy and hormonal treatment
  • Cardiophrenic lymph node metastasis in low-grade serous ovarian adenocarcinoma
  • Dramatic clinical response following dabrafenib and trametinib therapy in a T heavily pretreated low grade serous ovarian carcinoma patient with a BRAF V600E mutation
  • Dramatic response to Laetrile and cannabidiol (CBD) oil in a patient with T metastatic low grade serous ovarian carcinoma
  • Fine needle aspiration cytology of a nodal low-grade serous neoplasm: a case report of low-grade serous carcinoma arising from a serous borderline tumour with cyto-histological correlation
  • First evidence of a therapeutic effect of miransertib in a teenager with Proteus syndrome and ovarian carcinoma
  • Late recurrence of pStage 1 low-grade serous ovarian tumor presenting as a symptomatic bone metastasis: a case report
  • Low-grade ovarian serous carcinoma metastasis to the maxilla
  • Low-grade serous carcinoma (mullerian/ovarian type) of the paratestis presenting as diffuse metastatic disease of unknown origin: Case report of an uncommon tumor with an unusual presentation
  • Primary peritoneal low-grade serous carcinoma in a man: A case report and review of the literature
  • Rare metastatic patterns after malignant transformation of serous borderline tumor of the ovary
  • Recurrent low grade serous ovarian cancer in a 20 year old woman: A case from the Ohio State University College of Medicine
  • Response to trametinib in recurrent low-grade serous ovarian cancer with T NRAS mutation- A case report
  • Pulmonary tumour thrombotic microangiopathy as a cause of new-onset pulmonary hypertension in
    a patient with metastatic low-grade serous ovarian cancer

Clinical Trials

  • Hormonal Maintenance Therapy for Women With Low-Grade Serous Cancer of the Ovary or Peritoneum
  • Operability and chemotherapy responsiveness in advanced low-grade serous ovarian cancer. An analysis of the AGO Study Group metadatabase
  • Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study

Observational Research

  • Activity of bevacizumab-containing regimens in recurrent low-grade serous ovarian or peritoneal cancer: A single institution experience
  • Does tumor grade infuence the rate of lymph node metastasis in apparent early stage ovarian cancer?
  • Epidemiology of low-grade serous ovarian cancer
  • Impact of lympho-vascular space invasion on tumor characteristics and survival outcome of women with low-grade serous ovarian carcinoma
  • Increase in post-therapy tumor calcification on CT scan is not an indicator of response therapy in low-grade serous ovarian cancer
  • Invasive Epithelial Ovarian Cancer Survival by Histotype and Disease Stage
  • Obesity Is Associated With Worse Overall Survival in Women With Low-Grade Papillary Serous Epithelial Ovarian Cancer
  • Outcomes of Women With High-Grade and Low-Grade Advanced-Stage Serous Epithelial Ovarian Cancer
  • Patterns of Lymph Node Metastases in Apparent Stage I Low-Grade Epithelial Ovarian Cancer: A Multicenter Study
  • Pregnancy and oncologic outcomes of early stage low grade epithelial ovarian cancer after fertility sparing surgery: a retrospective study in one tertiary hospital of China
  • Primary cytoreductive surgery and adjuvant hormonal monotherapy in women with advanced low-grade serous ovarian carcinoma: Reducing overtreatment without compromising survival?
  • Recurrent low-grade serous ovarian carcinoma is relatively chemoresistant
  • Stage II to IV Low-grade Serous Carcinoma of the Ovary Is Associated With a Poor Prognosis: A Clinicopathologic Study of 32 Patients From a Population-based Tumour Registry
  • The clinical study of secondary cytoreductive surgery in the treatment of low grade serous ovarian cancer
  • The detrimental effect of adopting interval debulking surgery in advanced stage low-grade serous ovarian cancer
  • The Diagnostic Value of Serum CEA, CA-125, and ROMA Index in Low-Grade Serous Ovarian Cancer
  • The role of secondary cytoreduction in low-grade serous ovarian cancer or peritoneal cancer
  • Trends of low-grade serous ovarian carcinoma in the United States

Pre-clinical Research

  • An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity
  • A data science approach for the classification of low-grade and high-grade ovarian serous carcinomas
  • An immunophenotyping of Ovarian Cancer with Clinical and Immunological Significance
  • CAISMOV24, a new human low-grade serous ovarian carcinoma cell line
  • Connective tissue growth factor mediates TGF-β1-induced low-grade serous ovarian tumor cell apoptosis
  • Differences in MEK inhibitor efficacy in molecularly characterized low-grade serous ovarian cancer cell lines
  • Differential cyclooxygenase expression levels and survival associations in type I and type II ovarian tumors
  • EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas
  • Extreme Outlier Analysis Identifies Occult Mitogen- Activated Protein Kinase Pathway Mutations in Patients With Low-Grade Serous Ovarian Cancer
  • Gene expression profiles of ovarian low-grade serous carcinoma resemble those of fallopian tube epithelium
  • Hormone receptor expression profile of low-grade serous ovarian cancers
  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
  • Immunosuppressive microenvironment in low-grade serous ovarian carcinoma
  • Inhibition of nuclear factor-kappa B enhances the tumor growth of ovarian cancer cell line derived from a low-grade papillary serous carcinoma in p53- independent pathway
  • Interaction of ERα and NRF2 Impacts Survival in Ovarian Cancer Patients
  • Lack of MRE11-RAD50-NBS1 (MRN) complex detection occurs frequently in low-grade epithelial ovarian cancer
  • Loss of 1p36.33 Frequent in Low- Grade Serous Ovarian Cancer
  • Low frequency of BRAF and KRAS mutations in Chinese patients with low-grade serous carcinoma of the ovary
  • Markers of MEK inhibitor resistance in low-grade serous ovarian cancer: EGFR is a potential therapeutic target
  • Molecular alterations in indolent, aggressive and recurrent ovarian low-grade serous carcinoma
  • MyD88 and TLR4 Expression in Epithelial Ovarian Cancer
  • Mutation of NRAS is a rare genetic event in ovarian low-grade serous carcinoma
  • Prognostic significance of Ki-67 levels and hormone receptor expression in low-grade serous ovarian carcinoma: an investigation of the tumor bank ovarian cancer network
  • Synergistic effect of MEK inhibitor and metformin combination in low grade serous ovarian cancer
  • Tubal Origin of (Ovarian) Low-Grade Serous Carcinoma: A Gene Expression Profile Study

General research that may be of interest

  • Assessing the risk of pelvic and para-aortic nodal involvement in apparent early-stage ovarian cancer: A predictors- and nomogram-based analyses
  • Doctor, Does This Mean I’m Going to Starve to Death?
  • Fasting, Starving Cancer (from The Lancet)
  • Going to extremes: determinants of extraordinary response and survival in patients with cancer
  • Pathology of borderline and invasive cancers
  • Phytoestrogens in menopausal supplements induce ER-dependent cell proliferation and overcome breast cancer treatment in an in vitro breast cancer model
  • Prognostic indicators in ovarian serous borderline tumours
  • Reduction/Prevention of Lower Extremity Lymphedema after Pelvic and Para-aortic Lymphadenectomy for Patients with Gynecologic Malignancies

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